SolpaOne 1000mg Effervescent Tablets 12s

Always take this medicine exactly as described in this leaflet or as your doctor, pharmacist or nurse has told you. Check with your doctor, pharmacist or nurse if you are not sure. SolpaOne Effervescent Tablets are for oral administration and may be taken with or without food. Place the tablets in a full glass of water. Allow it to completely dissolve. Then drink the solution straight away. If you have doubts on the correct dose of SolpaOne Effervescent Tablets to use, please consult your doctor.

Adults and adolescents (aged 16 years and above) weighing more than 50kg:

Take one tablet every 6 hours as needed, up to a maximum of 4 tablets in 24 hours.

If the pain persists for more than 5 days or the fever lasts for more than 3 days, or gets worse or other symptoms appear, you should stop the treatment and consult a doctor.

If complaints persist or worsen, you should seek medical advice. Do not exceed the stated dose.

Kidney problems:

In moderate kidney problems: The usual dose is 500mg repeated every 6 hours. In severe kidney problems: The usual dose is 500mg repeated every 8 hours. Do not divide the 1000 mg tablet into two equal halves for the lower doses. Paracetamol tablets of lower strengths are available in the market.

Liver problems:

In case of problems with your liver please consult your doctor. Your doctor may decide to reduce the dose.
In chronic alcoholics, a dose of 2000mg per day should not be exceeded.

• Active Ingredient: Paracetamol 1000mg.
• Other Ingredients: Citric acid (anhydrous) (E330), povidone, sodium bicarbonate (E500), sodium saccharin (E954), sodium carbonate (anhydrous) (E500), simeticone (E900), polysorbate 80 (E443), aspartame (E951).

• Do not drink alcohol (e.g. wine, beer, spirits) whilst taking this medicine.
• This medicine is not suitable for patients weighing less than 50kg.
• Do not use paracetamol unless prescribed by your doctor if you have an addiction to alcohol or liver damage. If this applies to you, you must not take these tablets with alcohol.
• If you are already taking other pain medication containing paracetamol do not take these tablets without first speaking to your doctor or a pharmacist.
• Never take more SolpaOne 1000mg Effervescent Tablets than recommended. A higher dose does not increase pain relief; instead it can cause severe liver damage. The symptoms of liver damage occur first after a few days. It is important therefore that you contact your doctor as soon as possible if you have taken more
• SolpaOne 1000mg Effervescent Tablets than recommended in the leaflet.
• Do not use SolpaOne 1000mg Effervescent Tablets in children and adolescents below 16 years of age and under 50kg body weight.
• Paracetamol may extend the duration of action of chloramphenicol.
• Effects of SolpaOne 1000mg Effervescent Tablets may affect uric acid and blood sugar on laboratory tests.
• If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking any medicine. If necessary, SolpaOne Effervescent Tablets can be used during pregnancy. You should use the lowest possible dose that reduces your pain and/or your fever and use it for the shortest time possible. Contact your doctor if the pain and/or fever are not reduced or if you need to take the medicine more often. Paracetamol passes into breast milk. Therapeutic doses of Paracetamol can be administered during breastfeeding.
• This medicine contains 533.51mg sodium (main component of cooking/table salt) in each effervescent tablet. This is equivalent to 26.68% of the recommended maximum daily dietary intake of sodium for an adult.
• This medicine contains 10mg aspartame in each effervescent tablet. Aspartame is a source of phenylalanine. It may be harmful if you have phenylketonuria (PKU), a rare genetic disorder in which phenylalanine builds up because the body cannot remove it properly.

Do not take SolpaOne 1000mg Effervescent Tablets:

• If you are allergic to paracetamol or any of the ingredients of this medicine.

Talk to your doctor, pharmacist or nurse before taking SolpaOne 1000mg Effervescent Tablets:

• If you are suffering from kidney problems.
• If you are suffering from liver problems including liver problems due to excessive alcohol consumption.
• If you have Gilbert’s syndrome (mild jaundice).
• If you have hemolytic anemia (abnormal breakdown of red blood cells).
• If you are an asthmatic and sensitive to aspirin (acetylsalicylic acid).
• If you are suffering from dehydration or chronic malnutrition.
• If you are on paracetamol containing medicines.
• If you have fever after paracetamol therapy.
• If you suffer from glucose-6-phosphate dehydrogenase deficiency (enzyme deficiency).

Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines. Tell your doctor before you take SolpaOne 1000mg Effervescent Tablets if you are taking:

• Drugs to thin the blood (anti-coagulant drugs e.g. warfarin, other coumarins).
• Medicines used to relieve sickness (e.g. metoclopramide, domperidone).
• Medicines used to treat high cholesterol (cholestyramine).
• Probenecid (Medicine used to treat high levels of uric acid in the blood stream i.e gout).
• Medicine to treat fever or mild pain (aspirin (acetylsalicylic acid), salicylamide).
• Drugs such as rifampicin (drug that helps to fight infection) and some antiepileptics such as carbamazepine, phenytoin, phenobarbital, primidone (drugs used to treat or cure convulsions).
• Medicines used to treat epilepsy (lamotrigine).
• Medicines to treat tuberculosis (isoniazid).
• Flucloxacillin (antibiotic), due to a serious risk of blood and fluid abnormality (high anion gap metabolic acidosis) that must have urgent treatment and which may occur particularly in case of severe renal impairment, sepsis (when bacteria and their toxins circulate in the blood leading to organ damage), malnutrition, chronic alcoholism, and if the maximum daily doses of paracetamol are used.