Perrigo Heartburn & Acid Reflux Control 20mg Gastro-Resistant Capsules 14s

Always take this medicine exactly as described in the leaflet or as your doctor or pharmacist have told you. Check with your doctor or pharmacist if you are not sure.

• The recommended dose is one capsule a day.
• You can take your capsule at any time of the day either with food or on an empty stomach.
• Swallow your capsules whole with half a glass of water. Do not chew or crush the capsule. This is because the capsule contains coated pellets, which stop the medicine from being broken down by the acid in your stomach. It is important not to damage the pellets.
• Do not take more than this recommended dose of one capsule (20mg) a day, even if you don’t feel an improvement immediately.
• You may need to take the capsules for 2 or 3 days in a row before your reflux symptoms (for example, heartburn and acid regurgitation) get better.
• The treatment length is up to 14 days.
• When your reflux symptoms have completely gone you should stop taking this medicine.
• If your reflux symptoms get worse or do not improve after taking this medicine for 14 days in a row, you should consult a doctor.
• If you have persistent or longstanding, frequently recurring symptoms even after treatment with this medicine, you should contact your doctor.

• Active Ingredient: Esomeprazole 20mg.
• Other Ingredients: Sugar spheres (containing sucrose and maize starch), hypromellose, simethicone emulsion 30% (containing simethicone, polyoxyethylene sorbitan tristearate (polysorbate 65) (E436), methylcellulose, polyethylene glycol stearate, glycerides, xanthan gum, benzoic acid (E210), sorbic acid (E200), sulfuric acid and purified water), polysorbate 80, mannitol, diacetylated monoglycerides, talc, methacrylic acid-ethyl acrylate copolymer (1:1) dispersion 30 % (containing copolymer of methacrylic acid and ethyl acrylate, sodium lauryl sulfate and polysorbate 80), triethyl citrate and stearoyl macrogolglycerides. The capsule shell contains gelatin, yellow iron oxide (E172), black iron oxide (E172), titanium dioxide (E171), shellac, ammonia, potassium hydroxide and propylene glycol.

• Seek urgent medical attention if you experience chest pain with light-headedness, sweating, dizziness or shoulder pain with shortness of breath. This could be a sign of a serious condition with your heart.
• Perrigo Heartburn & Acid Reflux Control 20mg Gastro-Resistant Capsules should not be used by children and adolescents under 18 years of age.
• As a precautionary measure, you should preferably avoid the use of this medicine during pregnancy. You should not use this medicine during breastfeeding. If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.
• Perrigo Heartburn & Acid Reflux Control 20mg Gastro-Resistant Capsule have a low likelihood of affecting your ability to drive or use machines. However, side effects such as dizziness and visual disturbances may uncommonly occur. If affected, you should not drive or use machines.
• Perrigo Heartburn & Acid Reflux Control 20mg Gastro-Resistant Capsules contain sugar spheres, which contain sucrose, a type of sugar. If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.
• Perrigo Heartburn & Acid Reflux Control 20mg Gastro-Resistant Capsules contain benzoic acid This medicine contains 0.0018 mg benzoic acid in each capsule.
• Perrigo Heartburn & Acid Reflux Control 20mg Gastro-Resistant Capsules contain less than 1mmol sodium (23 mg) per capsule, that is to say essentially 'sodium-free'.

Do not take Perrigo Heartburn & Acid Reflux Control 20mg Gastro-Resistant Capsules:

• If you are allergic to esomeprazole or any of the other ingredients of this medicine.
• If you are allergic to medicines containing other proton pump inhibitors (e.g. pantoprazole, lansoprazole, rabeprazole or omeprazole).
• If you are taking a medicine containing nelfinavir (used to treat HIV infection).

Talk to your doctor before taking Perrigo Heartburn & Acid Reflux Control 20mg Gastro-Resistant Capsules if:

• You have had a stomach ulcer or stomach surgery in the past.
• You have been taking treatment continuously for reflux or heartburn for 4 or more weeks.
• You have jaundice (yellowing of skin or eyes) or severe liver problems.
• You have severe kidney problems.
• You are aged over 55 years and have new or recently changed reflux symptoms or need to take a non-prescription indigestion or heartburn remedy treatment every day.
• You have ever had a skin reaction after treatment with a medicine similar to this medicine that reduces stomach acid.

Tell your doctor before taking Perrigo Heartburn & Acid Reflux Control 20mg Gastro-Resistant Capsules if:

• You are due to have an endoscopy or a urea breath test.
• You are due to have a specific blood test (Chromogranin A).

Tell your doctor immediately before or after taking this medicine, if you notice any of the following symptoms, which could be a sign of another, more serious, disease:

• You lose a lot of weight for no reason.
• You have problems or pain when swallowing.
• You get stomach pain or signs of indigestion such as nausea, fullness, bloating especially after food intake.
• You begin to vomit food or blood, which may appear as dark coffee grounds in your vomit.
• You pass black stools (blood-stained faeces).
• You have severe or persistent diarrhoea; esomeprazole has been associated with a small increased risk of infectious diarrhoea.
• You get a rash on your skin, especially in areas exposed to the sun tell your doctor as soon as you can, as you may need to stop your treatment with this medicine. Remember to also mention any other ill-effects like pain in your joints.

Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines. This is because this medicine can affect the way some medicines work and some medicines can have an effect on it:

• Do not take this medicine if you are also taking a medicine containing nelfinavir (used to treat HIV infection).
• You should specifically tell your doctor or pharmacist if you are taking clopidogrel (used to prevent blood clots).
• Do not take this medicine with other medicines that limit the amount of acid produced in your stomach such as proton pump inhibitors (e.g. pantoprazole, lansoprazole, rabeprazole or omeprazole) or an H2 antagonist (e.g. ranitidine or famotidine).
• You may take this medicine with antacids (e.g. magaldrate, alginic acid, sodium bicarbonate, aluminium hydroxide, magnesium carbonate or combinations of these) if needed.
• Tell your doctor or pharmacist if you are taking any of the following medicines:
  
  • Ketoconazole and itraconazole (used to treat infections caused by a fungus).
  • Voriconazole (used to treat infections caused by a fungus) and clarithromycin (used to treat infections).
  • Your doctor may adjust your dose of this medicine if you also have severe liver problems and are treated for a long period of time.
  • Erlotinib (used to treat cancer).
  • Methotrexate (used to treat cancer and rheumatic disorders).
  • Digoxin (used for heart problems).
  • Atazanavir, saquinavir (used to treat HIV infection).
  • Citalopram, imipramine or clomipramine (used to treat depression).
  • Diazepam (used to treat anxiety, relax muscles or in epilepsy).
  • Phenytoin (used to treat epilepsy).
  • Medicines that are used to thin your blood, such as warfarin. Your doctor may need to monitor you
    when you start or stop taking this medicine.
  • Cilostazol (used to treat intermittent claudication - a condition where poor blood supply to the leg
    muscles causes pain and difficulty in walking).
  • Cisapride (used for indigestion and heartburn).
  • Rifampicin (used to treat tuberculosis).
  • Tacrolimus (in cases of organ transplantation).
  • St. John’s wort (Hypericum perforatum) (used to treat depression).